A 46-year-old armed patient at the Barnes-Jewish Hospital on Washington University’s Medical Campus was fatally shot by public safety officers after pulling a knife on health care professionals Thursday morning.

Prior to the shooting, the patient was in the exam room with his wife on the 14th floor of the Washington University Center for Advanced Medicine (CAM) before pushing his way out of the room, armed with two knives. Health care workers immediately responded by calling security, however when the officers arrived and patient refused to drop the knife, they shot him multiple times.

The St. Louis Children’s Hospital nearby was temporarily under lockdown after the shooting.

Chancellor Mark Wrighton responded to the events in an email addressed to the Washington University community to reassure students and faculty that there is no ongoing threat.

“The incident was contained to a small area of the CAM that was quickly secured, and there are no ongoing threats to patients, hospital staff, visitors or members of the university community,” Wrighton wrote.

The investigation has been turned over to the St. Louis Metropolitan Police Department.