Increasing energy dissipation by brown fat (thermogenesis) will:

1. Not cause a fever. Body temperature is tightly controlled, and fever is a mechanism involving an increase in body temp. setpoint in response to an immunological challenge (e.g. infection). Physical exercise causes an enormous (several fold) increase in heat production, and it does not cause a fever. Heat is disspated in the sweating process. Activation of brown fat can be achieved in animals (rats, mice, dogs, hamsters), and it induces weight loss and NO FEVER.

2. Not cause that big of an increase in heat dissipation and sweating as a ca. 20%-30% increase in energy dissipation (by brown fat activation) will be very significant on body weight on the long run BUT it is very minor compared to the 500%-1,000% increase in heat production-sweating taking place during moderate exercise.

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